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FRAX Fracture Risk Calculator

Calculate 10-year fracture risk using the WHO FRAX algorithm. Assess major osteoporotic fractures and hip fracture probability based on clinical risk factors.

Patient Information

Demographics

Clinical Risk Factors

Bone Mineral Density

Additional Risk Factors

FRAX Fracture Risk Assessment Results

Enter patient information to calculate 10-year fracture risk using the FRAX algorithm

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Important Medical Disclaimer

For Educational Purposes Only: This FRAX calculator is designed for educational and informational purposes. It implements the WHO FRAX algorithm but should not replace professional medical evaluation, diagnosis, or treatment decisions.

Clinical Interpretation Required: FRAX results provide population-based fracture probability estimates. Individual patient risk may vary significantly based on factors not captured in the algorithm. Healthcare providers should consider additional clinical factors, patient preferences, and current guidelines when making treatment recommendations.

Limitations: FRAX has specific limitations including validation primarily in postmenopausal women and older men, potential underestimation in certain ethnic groups, and inability to account for dose-dependent effects of some risk factors. Results should be interpreted within appropriate clinical context.

Professional Consultation: Always consult qualified healthcare professionals for personalized bone health assessment, interpretation of FRAX results, treatment decisions, and monitoring. This tool does not constitute medical advice and cannot replace clinical judgment.

Clinical Context & Implementation

WHO FRAX Algorithm

  • • Validated tool for 10-year fracture risk assessment
  • • Integrates clinical risk factors with or without BMD
  • • Country-specific calibration for epidemiologic accuracy
  • • Evidence-based foundation for treatment decisions
  • • Widely adopted in international osteoporosis guidelines

Clinical Applications

  • • Treatment threshold determination
  • • Cost-effectiveness analysis support
  • • Patient counseling and shared decision-making
  • • Population screening program implementation
  • • Clinical research risk stratification

Risk Factor Validation

  • • Previous fracture: 1.5-2x increased risk
  • • Parental hip fracture: 1.4-1.7x increased risk
  • • Glucocorticoids: 1.2-2.6x increased risk
  • • Rheumatoid arthritis: 1.4-2.4x increased risk
  • • Current smoking: 1.3-1.8x increased risk

Implementation Guidelines

  • • Age range: Validated for 40-90 years
  • • Treatment thresholds: Country-specific recommendations
  • • BMD integration: Femoral neck T-score preferred
  • • Reassessment: Every 1-2 years or major clinical changes
  • • Quality assurance: Regular calibration and validation

Evidence Base & Validation

1M+
Patients in validation cohorts
60+
Countries with FRAX models
200+
Peer-reviewed validation studies

FRAX has been extensively validated across diverse populations and is endorsed by major international organizations including WHO, IOF, NOF, and ISCD for fracture risk assessment and treatment decision-making.